mouse FBXL3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Fbxl3.
shAAV-259211
AAV-m-FBXL3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Fbxl3 (F-box and leucine-rich repeat protein 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AU041772; AW212966; FBK; Fbl3a; Fbxl3a; Ovtm; Play68
Description (Vector)
Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex involved in circadian clock function. The SCF(FBXL3) complex acts by mediating ubiquitination and subsequent degradation of CRY1 and CRY2. Recruiter of target protein that may recognize and bind to some phosphorylated proteins and promotes their ubiquitination and degradation.
Gene ID
50789
Gene Name (Vector)
F-box and leucine-rich repeat protein 3
Gene Symbol
Fbxl3
ORF Size (aa)
1287
ORF Size (bp)
1287 bp
RefSeq ID
NM_015822
RefSeq Synonyms
NM_015822, NM_001347601, NM_001347600, BC067203,
Species
mouse
UniGene ID
Mm.214746
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.