mouse FAIM3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Fcmr.
shAAV-258895
AAV-m-FAIM3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Fcmr (Fc fragment of IgM receptor). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1810037B05Rik; Faim3; FcmuR; Toso
Description (Vector)
FAIM3 may play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.
Gene ID
69169
Gene Name (Vector)
Fc fragment of IgM receptor
Gene Symbol
Fcmr
ORF Size (aa)
1269
ORF Size (bp)
1269 bp
RefSeq ID
NM_026976
RefSeq Synonyms
NM_026976, BC118505, BC116674,
Species
mouse
UniGene ID
Mm.46042
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.