mouse ESR2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Esr2.
shAAV-258716
AAV-m-ESR2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Esr2 (estrogen receptor 2 (beta)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ERbeta; ER[b]; Estrb
Description (Vector)
Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. Isoform beta-cx lacks ligand binding ability and has no or only very low ere binding activity resulting in the loss of ligand-dependent transactivation ability. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual.
Gene ID
13983
Gene Name (Vector)
estrogen receptor 2 (beta)
Gene Symbol
Esr2
ORF Size (aa)
1650
ORF Size (bp)
1650 bp
RefSeq ID
NM_207707
RefSeq Synonyms
NM_207707, NM_010157, BC145329, BC141075,
Species
mouse
UniGene ID
Mm.2561
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.