mouse ERN2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Ern2.
shAAV-258679
AAV-m-ERN2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Ern2 (endoplasmic reticulum (ER) to nucleus signalling 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Ern1; Ire1; ire1-beta; Ire1b; mIre1
Description (Vector)
Induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. Pro-apoptotic. Appears to play no role in the unfolded-protein response, unlike closely related proteins.
Gene ID
26918
Gene Name (Vector)
endoplasmic reticulum (ER) to nucleus signalling 2
Gene Symbol
Ern2
ORF Size (aa)
2733
ORF Size (bp)
2733 bp
RefSeq ID
NM_012016
RefSeq Synonyms
NM_012016, NM_001316689, BC109000, BC108999,
Species
mouse
UniGene ID
Mm.20452
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.