mouse ERCC6L shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Ercc6l.
shAAV-258638
AAV-m-ERCC6L-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Ercc6l (excision repair cross-complementing rodent repair deficiency complementation group 6 like). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BC004701; D330021P09Rik
Description (Vector)
DNA helicase that acts as an essential component of the spindle assembly checkpoint. Contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. Acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase.
Gene ID
236930
Gene Name (Vector)
excision repair cross-complementing rodent repair deficiency complementation group 6 like
Gene Symbol
Ercc6l
ORF Size (aa)
3723
ORF Size (bp)
3723 bp
RefSeq ID
NM_146235
RefSeq Synonyms
NM_146235, BC037660,
Species
mouse
UniGene ID
Mm.31911
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.