mouse EPOR shRNA silencing AAV

Name 
AAV-m-EPOR-shRNA
Cat No 
shAAV-258603
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Epor.

shAAV-258603
AAV-m-EPOR-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Epor (erythropoietin receptor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase|Function: Isoform EPOR-T acts as a dominant-negative receptor of EPOR-mediated signaling.
Gene ID
13857
Gene Name (Vector)
erythropoietin receptor
Gene Symbol
Epor
ORF Size (aa)
1524
ORF Size (bp)
1524 bp
RefSeq ID
NM_010149
RefSeq Synonyms
NM_010149, BC046282,
Species
mouse
UniGene ID
Mm.2653

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.