mouse ENSA shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Ensa.
shAAV-258397
AAV-m-ENSA-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Ensa (endosulfine alpha). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1700020C18Rik; 2610007F17Rik; AI451924
Description (Vector)
Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-67 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase (By similarity). Also acts as a stimulator of insulin secretion by interacting with sulfonylurea receptor (ABCC8), thereby preventing sulfonylurea from binding to its receptor and reducing K(ATP) channel currents.
Gene ID
56205
Gene Name (Vector)
endosulfine alpha
Gene Symbol
Ensa
ORF Size (aa)
219
RefSeq ID
NM_019561
RefSeq Synonyms
NM_019561, NM_001026212, BC059724, BC058802,
Species
mouse
UniGene ID
Mm.241365
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.