mouse DUOX2 shRNA silencing AAV

Name 
AAV-m-DUOX2-shRNA
Cat No 
shAAV-257518
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Duox2.

shAAV-257518
AAV-m-DUOX2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Duox2 (dual oxidase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
A430065P05Rik; LNOX2; NOXEF2; P138-TOX; THOX2
Description (Vector)
Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.
Gene ID
214593
Gene Name (Vector)
dual oxidase 2
Gene Symbol
Duox2
ORF Size (aa)
4554
ORF Size (bp)
4554 bp
RefSeq ID
NM_177610
RefSeq Synonyms
NM_177610, BC172692, BC172138, BC156280,
Species
mouse
UniGene ID
Mm.358846

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.