mouse DR1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Dr1.
shAAV-257447
AAV-m-DR1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Dr1 (down-regulator of transcription 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1700121L09Rik; Dr1l; NC2; NC2beta
Description (Vector)
The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.
Gene ID
13486
Gene Name (Vector)
down-regulator of transcription 1
Gene Symbol
Dr1
ORF Size (aa)
531
RefSeq ID
NM_026106
RefSeq Synonyms
NM_026106, BC013461,
Species
mouse
UniGene ID
Mm.303534
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.