mouse DOK4 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Dok4.
shAAV-257387
AAV-m-DOK4-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Dok4 (docking protein 4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway (By similarity). Putative link with downstream effectors of RET in neuronal differentiation. May be involved in the regulation of the immune response induced by T-cells.
Gene ID
114255
Gene Name (Vector)
docking protein 4
Gene Symbol
Dok4
ORF Size (aa)
978
ORF Size (bp)
978 bp
RefSeq ID
NM_053246
RefSeq Synonyms
NM_053246, BC004705,
Species
mouse
UniGene ID
Mm.203949
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.