mouse DOCK7 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Dock7.
shAAV-257377
AAV-m-DOCK7-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Dock7 (dedicator of cytokinesis 7). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
3110056M06Rik; Gm430
Description (Vector)
Functions as a guanine nucleotide exchange factor (GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. Does not have a GEF activity for CDC42. Required for STMN1 'Ser-15' phosphorylation during axon formation and consequently for neuronal polarization.
Gene ID
67299
Gene Name (Vector)
dedicator of cytokinesis 7
Gene Symbol
Dock7
ORF Size (aa)
3927
ORF Size (bp)
3927 bp
RefSeq ID
NM_026082
RefSeq Synonyms
NM_026082, NM_001290636, BC086672,
Species
mouse
UniGene ID
Mm.260623
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.