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mouse DOCK4 shRNA silencing AAV

Name 
AAV-m-DOCK4-shRNA
Cat No 
shAAV-257373
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Dock4.

shAAV-257373
AAV-m-DOCK4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Dock4 (dedicator of cytokinesis 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
5330406C03; 6330411N01Rik; AF263288; C030023J22; mKIAA0716
Description (Vector)
Involved in regulation of adherens junction between cells. Plays a role in cell migration. Functions as a guanine nucleotide exchange factor (GEF), which activates Rap1 small GTPase by exchanging bound GDP for free GTP.
Gene ID
238130
Gene Name (Vector)
dedicator of cytokinesis 4
Gene Symbol
Dock4
ORF Size (aa)
5934
ORF Size (bp)
5934 bp
RefSeq ID
NM_172803
RefSeq Synonyms
NM_172803, BC172663, BC156169, BC141138,
Species
mouse
UniGene ID
Mm.341423

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.