mouse DLG4 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Dlg4.
shAAV-257223
AAV-m-DLG4-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Dlg4 (discs, large homolog 4 (Drosophila)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Dlgh4; PSD-95; PSD95; SAP90; SAP90A
Description (Vector)
Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B (By similarity).
Gene ID
13385
Gene Name (Vector)
discs, large homolog 4 (Drosophila)
Gene Symbol
Dlg4
ORF Size (aa)
2166
ORF Size (bp)
2166 bp
RefSeq ID
NM_007864
RefSeq Synonyms
NM_007864, NM_001109752, BC014807,
Species
mouse
UniGene ID
Mm.27256
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.