mouse DGKQ shRNA silencing AAV

Cat. No: shAAV-257123

Availability: 6-8 weeks

Name: AAV-m-DGKQ-shRNA

This is an AAV expressing shRNA for silencing of Mouse Dgkq.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Dgkq
Gene Name: diacylglycerol kinase, theta
Gene ID: 110524
Gene Synonyms: 110kDa; DAGK; Dagk4; DAGK7; Dgkd
ORF Size: 2805 bp
RefSeq#: NM_199011
Gene Description: Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA). May regulate the activity of protein kinase C by controlling the balance between these two signaling lipids. Activated in the nucleus in response to alpha-thrombin and nerve growth factor (By similarity). May be involved in cAMP-induced activation of NR5A1 and subsequent steroidogenic gene transcription by delivering PA as ligand for NR5A1. Acts synergistically with NR5A1 on CYP17 transcriptional activity.
UniGene ID: Mm.260921