mouse DGKQ shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Dgkq.
shAAV-257123
AAV-m-DGKQ-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Dgkq (diacylglycerol kinase, theta). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
110kDa; DAGK; Dagk4; DAGK7; Dgkd
Description (Vector)
Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA). May regulate the activity of protein kinase C by controlling the balance between these two signaling lipids. Activated in the nucleus in response to alpha-thrombin and nerve growth factor (By similarity). May be involved in cAMP-induced activation of NR5A1 and subsequent steroidogenic gene transcription by delivering PA as ligand for NR5A1. Acts synergistically with NR5A1 on CYP17 transcriptional activity.
Gene ID
110524
Gene Name (Vector)
diacylglycerol kinase, theta
Gene Symbol
Dgkq
ORF Size (aa)
2805
ORF Size (bp)
2805 bp
RefSeq ID
NM_199011
RefSeq Synonyms
NM_199011, BC062929,
Species
mouse
UniGene ID
Mm.260921
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.