mouse DBNL shRNA silencing AAV

Cat. No: shAAV-256828

Availability: 4-5 weeks

Name: AAV-m-DBNL-shRNA

This is an AAV expressing shRNA for silencing of Mouse Dbnl.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Dbnl
Gene Name: drebrin-like
Gene ID: 13169
Gene Synonyms: Abp1; mAbp1; SH3P7
ORF Size: 1299 bp
RefSeq#: NM_013810
Gene Description: Actin-binding adapter protein. May act as a common effector of antigen receptor-signaling pathways in leukocytes. Its association with dynamin suggests that it may also connect the actin cytoskeleton to endocytic function. Acts as a key component of the immunological synapse that regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes. Binds to F-actin but is not involved in actin polymerization, capping or bundling. Does not bind G-actin.
UniGene ID: Mm.256925