mouse DBNL shRNA silencing AAV

Name 
AAV-m-DBNL-shRNA
Cat No 
shAAV-256828
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Dbnl.

shAAV-256828
AAV-m-DBNL-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Dbnl (drebrin-like). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Abp1; mAbp1; SH3P7
Description (Vector)
Actin-binding adapter protein. May act as a common effector of antigen receptor-signaling pathways in leukocytes. Its association with dynamin suggests that it may also connect the actin cytoskeleton to endocytic function. Acts as a key component of the immunological synapse that regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes. Binds to F-actin but is not involved in actin polymerization, capping or bundling. Does not bind G-actin.
Gene ID
13169
Gene Name (Vector)
drebrin-like
Gene Symbol
Dbnl
ORF Size (aa)
1299
ORF Size (bp)
1299 bp
RefSeq ID
NM_013810
RefSeq Synonyms
NM_013810, NM_001146309, NM_001146308, BC046430,
Species
mouse
UniGene ID
Mm.256925

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.