mouse CTLA4 shRNA silencing AAV

Name 
AAV-m-CTLA4-shRNA
Cat No 
shAAV-256310
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Ctla4.

shAAV-256310
AAV-m-CTLA4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Ctla4 (cytotoxic T-lymphocyte-associated protein 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Cd152; Ctla-4; Ly-56
Description (Vector)
Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.
Gene ID
12477
Gene Name (Vector)
cytotoxic T-lymphocyte-associated protein 4
Gene Symbol
Ctla4
ORF Size (aa)
672
RefSeq ID
NM_009843
RefSeq Synonyms
NM_009843, NM_001281976, BC052683, BC042741,
Species
mouse
UniGene ID
Mm.390

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.