mouse CRX shRNA silencing AAV

Name 
AAV-m-CRX-shRNA
Cat No 
shAAV-256158
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Crx.

shAAV-256158
AAV-m-CRX-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Crx (cone-rod homeobox). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Crx1
Description (Vector)
Binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, e.g. NRL and RX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors.
Gene ID
12951
Gene Name (Vector)
cone-rod homeobox
Gene Symbol
Crx
ORF Size (aa)
900
ORF Size (bp)
900 bp
RefSeq ID
NM_007770
RefSeq Synonyms
NM_007770, NM_001113330, BC016502,
Species
mouse
UniGene ID
Mm.441911

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.