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mouse COMT1 shRNA silencing AAV

Name 
AAV-m-COMT1-shRNA
Cat No 
shAAV-255903
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Comt.

shAAV-255903
AAV-m-COMT1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Comt (catechol-O-methyltransferase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Comt1; D16Wsu103e; D330014B15Rik
Description (Vector)
Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol.
Gene ID
12846
Gene Name (Vector)
catechol-O-methyltransferase
Gene Symbol
Comt
ORF Size (aa)
798
ORF Size (bp)
798 bp
RefSeq ID
NM_007744
RefSeq Synonyms
NM_007744, NM_001111063, NM_001111062, BC010402,
Species
mouse
UniGene ID
Mm.100940

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.