mouse CNGA4 shRNA silencing AAV

Name
AAV-m-CNGA4-shRNA

Cat No
shAAV-255747

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Mouse Cnga4.

shAAV-255747

AAV-m-CNGA4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Cnga4 (cyclic nucleotide gated channel alpha 4). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

Second messenger, cAMP, causes the opening of cation-selective cyclic nucleotide-gated (CNG) channels and depolarization of the neuron (olfactory sensory neurons, OSNs). CNGA4 is the modulatory subunit of this channel which is known to play a central role in the transduction of odorant signals and subsequent adaptation. By accelerating the calcium-mediated negative feedback in olfactory signaling it allows rapid adaptation to odor stimulation and extends its range of odor detection (By similarity).

Gene ID

233649

Gene Name (Vector)

cyclic nucleotide gated channel alpha 4

Gene Symbol

Cnga4

ORF Size (aa)

1419

ORF Size (bp)

1419 bp

RefSeq ID

NM_001033317

RefSeq Synonyms

NM_001033317, BC107348, BC107347,

Species

mouse

UniGene ID

Mm.99556

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.