mouse CLK1 shRNA silencing AAV

Name
AAV-m-CLK1-shRNA

Cat No
shAAV-255664

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Mouse Clk1.

shAAV-255664

AAV-m-CLK1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Clk1 (CDC-like kinase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

STY

Description (Vector)

Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates: SRSF1, SRSF3 and PTPN1. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells and adenovirus E1A pre-mRNA.

Gene ID

12747

Gene Name (Vector)

CDC-like kinase 1

Gene Symbol

Clk1

ORF Size (aa)

1452

ORF Size (bp)

1452 bp

RefSeq ID

NM_001042634

RefSeq Synonyms

NM_001042634, BC160357,

Species

mouse

UniGene ID

Mm.1761

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.