mouse CLK1 shRNA silencing AAV

Cat. No: shAAV-255664

Availability: 6-8 weeks

Name: AAV-m-CLK1-shRNA

This is an AAV expressing shRNA for silencing of Mouse Clk1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Clk1
Gene Name: CDC-like kinase 1
Gene ID: 12747
Gene Synonyms: STY
ORF Size: 1452 bp
RefSeq#: NM_001042634
Gene Description: Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates: SRSF1, SRSF3 and PTPN1. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells and adenovirus E1A pre-mRNA.
UniGene ID: Mm.1761