mouse CLCN3 shRNA silencing AAV

Name
AAV-m-CLCN3-shRNA

Cat No
shAAV-255571

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Mouse Clcn3.

shAAV-255571

AAV-m-CLCN3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Clcn3 (chloride channel, voltage-sensitive 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Clc3

Description (Vector)

Mediates the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the endosome and synaptic vesicle lumen, and may thereby affect vesicle trafficking and exocytosis. May play an important role in neuronal cell function through regulation of membrane excitability by protein kinase C. It could help neuronal cells to establish short-term memory.

Gene ID

12725

Gene Name (Vector)

chloride channel, voltage-sensitive 3

Gene Symbol

Clcn3

ORF Size (aa)

2376

ORF Size (bp)

2376 bp

RefSeq ID

NM_007711

RefSeq Synonyms

NM_173876, NM_173874, NM_173873, NM_007711, BC057133,

Species

mouse

UniGene ID

Mm.259751

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.