mouse CHRDL2 shRNA silencing AAV

Name 
AAV-m-CHRDL2-shRNA
Cat No 
shAAV-255435
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Chrdl2.

shAAV-255435
AAV-m-CHRDL2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Chrdl2 (chordin-like 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
1810022C01Rik; Chl2
Description (Vector)
CHRDL2 may inhibits BMPs activity by blocking their interaction with their receptors. Has a negative regulator effect on the cartilage formation/regeneration from immature mesenchymal cells, by preventing or reducing the rate of matrix accumulation (By similarity). Implicated in tumor angiogenesis. May play a role during myoblast and osteoblast differentiation, and maturation.
Gene ID
69121
Gene Name (Vector)
chordin-like 2
Gene Symbol
Chrdl2
ORF Size (aa)
1281
ORF Size (bp)
1281 bp
RefSeq ID
NM_133709
RefSeq Synonyms
NM_133709, NM_001291320, BC019399,
Species
mouse
UniGene ID
Mm.285295

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.