mouse CHORDC1 shRNA silencing AAV

Name
AAV-m-CHORDC1-shRNA

Cat No
shAAV-255430

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Mouse Chordc1.

shAAV-255430

AAV-m-CHORDC1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Chordc1 (cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

1110001O09Rik; AA409036; Chp-1; morgana

Description (Vector)

Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. Proposed to act as co-chaperone for HSP90. May play a role in the regulation of NOD1 via a HSP90 chaperone complex. In vitro, has intrinsic chaperone activity. This function may be achieved by inhibiting association of ROCK2 with NPM1. Involved in stress response. Prevents tumorigenesis.

Gene ID

66917

Gene Name (Vector)

cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1

Gene Symbol

Chordc1

ORF Size (aa)

996

RefSeq ID

NM_025844

RefSeq Synonyms

NM_025844, BC018374,

Species

mouse

UniGene ID

Mm.476826

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.