mouse CHL1 shRNA silencing AAV

Name
AAV-m-CHL1-shRNA

Cat No
shAAV-255405

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Mouse Chl1.

shAAV-255405

AAV-m-CHL1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Chl1 (cell adhesion molecule L1-like). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

A530023M13Rik; AI465420; CALL; LICAM2

Description (Vector)

Extracellular matrix and cell adhesion protein that plays a role in nervous system development and in synaptic plasticity. Both soluble and membranous forms promote neurite outgrowth of cerebellar and hippocampal neurons and suppress neuronal cell death. Plays a role in neuronal positioning of pyramidal neurons and in regulation of both the number of interneurons and the efficacy of GABAergic synapses. May play a role in regulating cell migration in nerve regeneration and cortical development. Potentiates integrin-dependent cell migration towards extracellular matrix proteins. Recruits ANK3 to the plasma membrane (By similarity).

Gene ID

12661

Gene Name (Vector)

cell adhesion molecule L1-like

Gene Symbol

Chl1

ORF Size (aa)

3630

ORF Size (bp)

3630 bp

RefSeq ID

NM_007697

RefSeq Synonyms

NM_007697, BC131671, BC131670,

Species

mouse

UniGene ID

Mm.251288

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.