mouse CH25H shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Ch25h.
shAAV-255354
AAV-m-CH25H-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Ch25h (cholesterol 25-hydroxylase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AI462618; m25OH
Description (Vector)
Catalyzes the formation of 25-hydroxycholesterol from cholesterol, leading to repress cholesterol biosynthetic enzymes. May play an important role in regulating lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element binding protein (SREBP) processing. In testis, production of 25-hydroxycholesterol by macrophages may play a role in Leydig cell differentiation.
Gene ID
12642
Gene Name (Vector)
cholesterol 25-hydroxylase
Gene Symbol
Ch25h
ORF Size (aa)
897
ORF Size (bp)
897 bp
RefSeq ID
NM_009890
RefSeq Synonyms
NM_009890, BC039919,
Species
mouse
UniGene ID
Mm.30824
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.