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mouse CDCA8 shRNA silencing AAV

Name 
AAV-m-CDCA8-shRNA
Cat No 
shAAV-255126
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Cdca8.

shAAV-255126
AAV-m-CDCA8-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Cdca8 (cell division cycle associated 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
4831429J16Rik; AU044747; BOR; Borealin; D4Ertd421e; DasraB; MESRGP
Description (Vector)
Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, it may be required to direct the CPC to centromeric DNA. Major effector of the TTK kinase in the control of attachment-error-correction and chromosome alignment.
Gene ID
52276
Gene Name (Vector)
cell division cycle associated 8
Gene Symbol
Cdca8
ORF Size (aa)
489
ORF Size (bp)
489 bp
RefSeq ID
NM_026560
RefSeq Synonyms
NM_026560, BC068181,
Species
mouse
UniGene ID
Mm.28038

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.