mouse CD74 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Cd74.
shAAV-255043
AAV-m-CD74-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Cd74 (CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CLIP; DHLAG; HLADG; Ia-GAMMA; Ii
Description (Vector)
Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF.
Gene ID
16149
Gene Name (Vector)
CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
Gene Symbol
Cd74
ORF Size (aa)
840
RefSeq ID
NM_010545
RefSeq Synonyms
NM_010545, NM_001042605, BC096435, BC003476,
Species
mouse
UniGene ID
Mm.439737
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.