mouse CCL22 shRNA silencing AAV

Name
AAV-m-CCL22-shRNA

Cat No
shAAV-254832

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Mouse Ccl22.

shAAV-254832

AAV-m-CCL22-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Ccl22 (chemokine (C-C motif) ligand 22). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ABCD-1; DCBCK; MDC; Scya22

Description (Vector)

CCL22 may play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Chemotactic for monocytes, dendritic cells and natural killer cells. Mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemoattractant activity for neutrophils, eosinophils, and resting T-lymphocytes. Binds to CCR4. Processed forms MDC(3-69), MDC(5-69) and MDC(7-69) seem not be active.

Gene ID

20299

Gene Name (Vector)

chemokine (C-C motif) ligand 22

Gene Symbol

Ccl22

ORF Size (aa)

279

RefSeq ID

NM_009137

RefSeq Synonyms

NM_009137, BC012658,

Species

mouse

UniGene ID

Mm.12895

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.