mouse CACNA2D2 shRNA silencing AAV

Name 
AAV-m-CACNA2D2-shRNA
Cat No 
shAAV-254370
Availability
Immediate
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Cacna2d2.

shAAV-254370
AAV-m-CACNA2D2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Cacna2d2 (calcium channel, voltage-dependent, alpha 2/delta subunit 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
58
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
a2d2; Cacna2d; du; mKIAA0558; td; torpid
Description (Vector)
The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Acts as a regulatory subunit for P/Q-type calcium channel (CACNA1A), N-type (CACNA1B), L-type (CACNA1C OR CACNA1D) and possibly T-type (CACNA1G). Overexpression induces apoptosis.
Gene ID
56808
Gene Name (Vector)
calcium channel, voltage-dependent, alpha 2/delta subunit 2
Gene Symbol
Cacna2d2
ORF Size (aa)
3444
ORF Size (bp)
3444 bp
RefSeq ID
NM_020263
RefSeq Synonyms
NM_020263, NM_001174050, NM_001174049, NM_001174048, NM_001174047, BC158058, BC056389,
Species
mouse
UniGene ID
Mm.273084

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.