mouse C1QC shRNA silencing AAV

Name
AAV-m-C1QC-shRNA

Cat No
shAAV-254225

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Mouse C1qc.

shAAV-254225

AAV-m-C1QC-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse C1qc (complement component 1, q subcomponent, C chain). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AI385742; C1qg; Ciqc

Description (Vector)

C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.

Gene ID

12262

Gene Name (Vector)

complement component 1, q subcomponent, C chain

Gene Symbol

C1qc

ORF Size (aa)

741

ORF Size (bp)

741 bp

RefSeq ID

NM_007574

RefSeq Synonyms

NM_007574, BC075724, BC054443, BC043945,

Species

mouse

UniGene ID

Mm.439732

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.