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mouse BST2 shRNA silencing AAV

Name 
AAV-m-BST2-shRNA
Cat No 
shAAV-254117
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Bst2.

shAAV-254117
AAV-m-BST2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Bst2 (bone marrow stromal cell antigen 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2310015I10Rik; Bst-2; C87040; CD317; DAMP-1; GREG
Description (Vector)
BST2 may be involved in the sorting of secreted proteins (By similarity). May be involved in pre-B-cell growth. Antiretroviral defense protein, that blocks release of enveloped virus from the cell surface. Active against at least four virus families: retroviruses, filoviruses, arenaviruses, and herpesviruses. Depleted unpon HIV-1 infection by viral VPU protein through 20S proteasome degradation. Depleted upon infection by human Kaposi's sarcoma-associated herpesvirus (KSHV) through ubiquitination and subsequent degradation. May play a role in B-cell activation in rheumatoid arthritis.
Gene ID
69550
Gene Name (Vector)
bone marrow stromal cell antigen 2
Gene Symbol
Bst2
ORF Size (aa)
519
ORF Size (bp)
519 bp
RefSeq ID
NM_198095
RefSeq Synonyms
NM_198095, BC087949, BC056638, BC027328,
Species
mouse
UniGene ID
Mm.260325

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.