mouse BRUNOL6 shRNA silencing AAV

Name
AAV-m-BRUNOL6-shRNA

Cat No
shAAV-254102

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Mouse Celf6.

shAAV-254102

AAV-m-BRUNOL6-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Celf6 (CUGBP, Elav-like family member 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

6330569O16Rik; Brunol6

Description (Vector)

RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of TNNT2 in a muscle-specific splicing enhancer (MSE)-dependent manner. Promotes also exon exclusion of INSR pre-mRNA.

Gene ID

76183

Gene Name (Vector)

CUGBP, Elav-like family member 6

Gene Symbol

Celf6

ORF Size (aa)

1038

RefSeq ID

NM_175235

RefSeq Synonyms

NM_175235, NM_001311092, BC057083, BC052406,

Species

mouse

UniGene ID

Mm.265415

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.