mouse BMPR2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Bmpr2.
shAAV-254033
AAV-m-BMPR2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Bmpr2 (bone morphogenetic protein receptor, type II (serine/threonine kinase)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2610024H22Rik; AL117858; AW546137; BB189135; BMP-2; BMPR-2; BMPR-II; BMPRII; BRK-3; Gm20272
Description (Vector)
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP-7, BMP-2 and, less efficiently, BMP-4. Binding is weak but enhanced by the presence of type I receptors for BMPs.
Gene ID
12168
Gene Name (Vector)
bone morphogenetic protein receptor, type II (serine/threonine kinase)
Gene Symbol
Bmpr2
ORF Size (aa)
3117
ORF Size (bp)
3117 bp
RefSeq ID
NM_007561
RefSeq Synonyms
NM_007561, BC156868, BC148339,
Species
mouse
UniGene ID
Mm.391654
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.