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mouse BMI1 shRNA silencing AAV

Name 
AAV-m-BMI1-shRNA
Cat No 
shAAV-254009
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Bmi1.

shAAV-254009
AAV-m-BMI1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Bmi1 (Bmi1 polycomb ring finger oncogene). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AW546694; Bmi-1; Pcgf4
Description (Vector)
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
Gene ID
12151
Gene Name (Vector)
Bmi1 polycomb ring finger oncogene
Gene Symbol
Bmi1
ORF Size (aa)
975
ORF Size (bp)
975 bp
RefSeq ID
NM_007552
RefSeq Synonyms
NM_007552, BC056384, BC053708,
Species
mouse
UniGene ID
Mm.289584

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.