mouse BID shRNA silencing AAV

Name 
AAV-m-BID-shRNA
Cat No 
shAAV-253984
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Bid.

shAAV-253984
AAV-m-BID-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Bid (BH3 interacting domain death agonist). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2700049M22Rik; AI875481; AU022477; BH3-interacting domain death agonist; BID; p22 BID
Description (eCommerce)
BID (BH3-interacting domain death agonist) can mediate both apoptotic and pro-survival signals in response to DNA damage. BID is phosphorylated by ATM in response to DNA damage and may play a role in the cell’s decision of whether to live or die based on the extent of damage.
Description (Vector)
The major proteolytic product p15 BID allows the release of cytochrome c (By similarity). Isoform 1, isoform 2 and isoform 4 induce ICE-like proteases and apoptosis. Isoform 3 does not induce apoptosis. Counters the protective effect of Bcl-2.
Gene ID
12122
Gene Name (eCommerce)
BH3 interacting domain death agonist
Gene Name (Vector)
BH3 interacting domain death agonist
Gene Symbol
Bid
NCBI Taxonomy ID (eCommerce)
10090.0
ORF Size (aa)
588
Protein Name (eCommerce)
BH3-interacting domain death agonist
RefSeq ID
NM_007544
RefSeq Synonyms
NM_007544, BC002031,
Research Areas
Phospho-specific
Research Areas (Faceted)
cell_biology
Species
mouse
Target Sentence
BID (BH3-interacting domain death agonist) can mediate both apoptotic and pro-survival signals in response to DNA damage. BID is phosphorylated by ATM in response to DNA damage and may play a role in the cell’s decision of whether to live or die based on the extent of damage.
UniGene ID
Mm.235081
UniProt ID (eCommerce)
P70444

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.