mouse BC019943 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse TTI2.
shAAV-253710
AAV-m-BC019943-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse TTI2 (TELO2 interacting protein 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs.
Gene ID
234138
Gene Name (Vector)
TELO2 interacting protein 2
Gene Symbol
TTI2
ORF Size (aa)
1539
ORF Size (bp)
1539 bp
RefSeq ID
NM_144927
RefSeq Synonyms
NM_144927, NM_001199988, NM_001112729, BC019943,
Species
mouse
UniGene ID
Mm.349800
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.