mouse BAX shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Bax.
shAAV-253636
AAV-m-BAX-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Bax (BCL2-associated X protein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
Gene ID
12028
Gene Name (Vector)
BCL2-associated X protein
Gene Symbol
Bax
ORF Size (aa)
579
ORF Size (bp)
579 bp
RefSeq ID
NM_007527
RefSeq Synonyms
NM_007527, BC053380, BC018228,
Species
mouse
UniGene ID
Mm.19904
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.