mouse B3GNT5 shRNA silencing AAV

Name
AAV-m-B3GNT5-shRNA

Cat No
shAAV-253531

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Mouse B3gnt5.

shAAV-253531

AAV-m-B3GNT5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse B3gnt5 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

beta3GnT5

Description (Vector)

Beta-1,3-N-acetylglucosaminyltransferase that plays a key role in the synthesis of lacto- or neolacto-series carbohydrate chains on glycolipids, notably by participating in biosynthesis of HNK-1 and Lewis X carbohydrate structures. Has strong activity toward lactosylceramide (LacCer) and neolactotetraosylceramide (nLc(4)Cer; paragloboside), resulting in the synthesis of Lc(3)Cer and neolactopentaosylceramide (nLc(5)Cer), respectively. Probably plays a central role in regulating neolacto-series glycolipid synthesis during embryonic development.

Gene ID

108105

Gene Name (Vector)

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5

Gene Symbol

B3gnt5

ORF Size (aa)

1131

ORF Size (bp)

1131 bp

RefSeq ID

NM_054052

RefSeq Synonyms

NM_054052, NM_001159408, NM_001159407, BC063076,

Species

mouse

UniGene ID

Mm.33935

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.