mouse AWAT1 shRNA silencing AAV

Name
AAV-m-AWAT1-shRNA

Cat No
shAAV-253464

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Mouse Awat1.

shAAV-253464

AAV-m-AWAT1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Awat1 (acyl-CoA wax alcohol acyltransferase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Dgat2l3

Description (Vector)

Acyltransferase that predominantly esterify long chain (wax) alcohols with acyl-CoA-derived fatty acids to produce wax esters. Wax esters are enriched in sebum, suggesting that it plays a central role in lipid metabolism in skin. Has a preference for arachidyl alcohol as well as decyl alcohol, demonstrating its relatively poor activity using saturated long chain alcohols (C16, C18, and C20).

Gene ID

245533

Gene Name (Vector)

acyl-CoA wax alcohol acyltransferase 1

Gene Symbol

Awat1

ORF Size (aa)

987

ORF Size (bp)

987 bp

RefSeq ID

NM_001081136

RefSeq Synonyms

NM_001081136, BC147832, BC147829, BC147683, BC147680,

Species

mouse

UniGene ID

Mm.77759

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.