mouse ATF6 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Atf6.
shAAV-253211
AAV-m-ATF6-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Atf6 (activating transcription factor 6). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
9130025P16Rik; 9630036G24; AA789574; Atf6alpha; ESTM49
Description (Vector)
Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Binds DNA on the 5'-CCAC[GA]-3'half of the ER stress response element (ERSE) (5'-CCAAT-N(9)-CCAC[GA]-3') and of ERSE II (5'-ATTGG-N-CCACG-3'). Binding to ERSE requires binding of NF-Y to ERSE. Could also be involved in activation of transcription by the serum response factor.
Gene ID
226641
Gene Name (Vector)
activating transcription factor 6
Gene Symbol
Atf6
ORF Size (aa)
1971
ORF Size (bp)
1971 bp
RefSeq ID
NM_001081304
RefSeq Synonyms
NM_001081304, BC141028,
Species
mouse
UniGene ID
Mm.377046
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.