mouse ARNT shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Arnt.
shAAV-253058
AAV-m-ARNT-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Arnt (aryl hydrocarbon receptor nuclear translocator). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
bHLHe2; D3Ertd557e; Drnt; ESTM42; Hif1b; mKIAA4051; W08714
Description (Vector)
Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia.
Gene ID
11863
Gene Name (Vector)
aryl hydrocarbon receptor nuclear translocator
Gene Symbol
Arnt
ORF Size (aa)
2376
ORF Size (bp)
2376 bp
RefSeq ID
NM_009709
RefSeq Synonyms
NM_009709, NM_001037737, BC012870,
Species
mouse
UniGene ID
Mm.250265
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.