mouse ARHGEF12 shRNA silencing AAV

Name 
AAV-m-ARHGEF12-shRNA
Cat No 
shAAV-252967
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Arhgef12.

shAAV-252967
AAV-m-ARHGEF12-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Arhgef12 (Rho guanine nucleotide exchange factor (GEF) 12). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2310014B11Rik; AU019857; Larg; mKIAA0382
Description (Vector)
ARHGEF12 may play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13.
Gene ID
69632
Gene Name (Vector)
Rho guanine nucleotide exchange factor (GEF) 12
Gene Symbol
Arhgef12
ORF Size (aa)
4632
ORF Size (bp)
4632 bp
RefSeq ID
NM_027144
RefSeq Synonyms
NM_027144, BC156558,
Species
mouse
UniGene ID
Mm.275266

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.