mouse AHRR shRNA silencing AAV

Name
AAV-m-AHRR-shRNA

Cat No
shAAV-252280

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Mouse Ahrr.

shAAV-252280

AAV-m-AHRR-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Ahrr (aryl-hydrocarbon receptor repressor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

mKIAA1234

Description (Vector)

Mediates dioxin toxicity and is involved in regulation of cell growth and differentiation. Represses the transcription activity of AHR by competing with this transcription factor for heterodimer formation with the ARNT and subsequently binding to the xenobiotic response element (XRE) sequence present in the promoter regulatory region of variety of genes. Represses CYP1A1 by binding the XRE sequence and recruiting ANKRA2, HDAC4 and/or HDAC5. Autoregulates its expression by associating with its own XRE site.

Gene ID

11624

Gene Name (Vector)

aryl-hydrocarbon receptor repressor

Gene Symbol

Ahrr

ORF Size (aa)

1722

ORF Size (bp)

1722 bp

RefSeq ID

NM_009644

RefSeq Synonyms

NM_009644, NM_001317351, BC118534,

Species

mouse

UniGene ID

Mm.290446

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.