mouse ADRA1B shRNA silencing AAV

Name 
AAV-m-ADRA1B-shRNA
Cat No 
shAAV-252164
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Adra1b.

shAAV-252164
AAV-m-ADRA1B-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Adra1b (adrenergic receptor, alpha 1b). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
[a]1b
Description (Vector)
This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes.
Gene ID
11548
Gene Name (Vector)
adrenergic receptor, alpha 1b
Gene Symbol
Adra1b
ORF Size (aa)
1548
ORF Size (bp)
1548 bp
RefSeq ID
NM_007416
RefSeq Synonyms
NM_007416, NM_001284381, NM_001284380, BC138654, BC138653,
Species
mouse
UniGene ID
Mm.39086

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.