mouse 4930547N16RIK shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Parpbp.
shAAV-251165
AAV-m-4930547N16RIK-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Parpbp (PARP1 binding protein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
4930547N16Rik; AI503644; PARI
Description (Vector)
Required to suppress inappropriate homologous recombination, thereby playing a central role DNA repair and in the maintenance of genomic stability. Antagonizes homologous recombination by interfering with the formation of the RAD51-DNA homologous recombination structure. Binds single-strand DNA and poly(A) homopolymers. Positively regulate the poly(ADP-ribosyl)ation activity of PARP1; however such function may be indirect.
Gene ID
75317
Gene Name (Vector)
PARP1 binding protein
Gene Symbol
Parpbp
ORF Size (aa)
1722
ORF Size (bp)
1722 bp
RefSeq ID
NM_029249
RefSeq Synonyms
NM_029249, BC070476,
Species
mouse
UniGene ID
Mm.179378
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.