mouse SRRM4 shRNA silencing AAV

Name
AAV-m-SRRM4-shRNA

Cat No
shAAV-250201

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Mouse Srrm4.

shAAV-250201

AAV-m-SRRM4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Srrm4 (serine/arginine repetitive matrix 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

1500001A10Rik; B230202K19Rik; bv; mKIAA1853; nSR100

Description (Vector)

Splicing factor specifically required for neural cell differentiation. Acts in conjuction with nPTB/PTBP2 by binding directly to its regulated target transcripts and promotes neural-specific exon inclusion in many genes that function in neural cell differentiation. Required to promote the inclusion of neural-specific exon 10 in nPTB/PTBP2, leading to increased expression of neural-specific nPTB/PTBP2. Also promotes the inclusion of exon 16 in DAAM1 in neuron extracts (By similarity).

Gene ID

68955

Gene Name (Vector)

serine/arginine repetitive matrix 4

Gene Symbol

Srrm4

ORF Size (aa)

1827

ORF Size (bp)

1827 bp

RefSeq ID

NM_026886

RefSeq Synonyms

NM_026886, BC056392,

Species

mouse

UniGene ID

Mm.146779

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.