mouse 1110032A04RIK shRNA silencing AAV

Name 
AAV-m-1110032A04RIK-shRNA
Cat No 
shAAV-250141
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Sptssb.

shAAV-250141
AAV-m-1110032A04RIK-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Sptssb (serine palmitoyltransferase, small subunit B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
1110032A04Rik; ADMP; Sssptb
Description (Vector)
Stimulates the activity of serine palmitoyltransferase (SPT). The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference, complexes with this subunit showing a clear preference for longer acyl-CoAs. The SPTLC1-SPTLC2-SPTSSB complex shows a strong preference for C18-CoA substrate, while the SPTLC1-SPTLC3-SPTSSB isozyme displays an ability to use a broader range of acyl-CoAs, without apparent preference. May play a role in signal transduction.
Gene ID
66183
Gene Name (Vector)
serine palmitoyltransferase, small subunit B
Gene Symbol
Sptssb
ORF Size (aa)
231
RefSeq ID
NM_133675
RefSeq Synonyms
NM_133675, NM_001286959, NM_001164210, BC022628,
Species
mouse
UniGene ID
Mm.45481

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.