mouse 1110008J03RIK shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Rita1.
shAAV-250115
AAV-m-1110008J03RIK-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Rita1 (RBPJ interacting and tubulin associated 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1110008J03Rik; AI853657; C86297; Rita
Description (Vector)
Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis.
Gene ID
100764
Gene Name (Vector)
RBPJ interacting and tubulin associated 1
Gene Symbol
Rita1
ORF Size (aa)
762
RefSeq ID
NM_029096
RefSeq Synonyms
NM_133908, NM_029096, BC021365,
Species
mouse
UniGene ID
Mm.9654
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.