human PCLO shRNA silencing AAV

Name 
AAV-h-PCLO-shRNA
Cat No 
shAAV-233943
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PCLO.

shAAV-233943
AAV-h-PCLO-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PCLO (piccolo presynaptic cytomatrix protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ACZ; PCH3
Description (Vector)
PCLO is part of the presynaptic cytoskeletal matrix, which is involved in establishing active synaptic zones and in synaptic vesicle trafficking. Variations in this gene have been associated with bipolar disorder and major depressive disorder. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
27445
Gene Name (Vector)
piccolo presynaptic cytomatrix protein
Gene Symbol
PCLO
HGNC ID
HGNC:13406
ORF Size (aa)
1071
ORF Size (bp)
1071 bp
RefSeq ID
NM_033026
RefSeq Synonyms
NM_033026, NM_014510, BC001304,
Species
human

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.