human MLLT6 shRNA silencing AAV

Name
AAV-h-MLLT6-shRNA

Cat No
shAAV-233935

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human MLLT6.

shAAV-233935

AAV-h-MLLT6-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MLLT6 (MLLT6, PHD finger domain containing). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AF17; ALL1-fused gene from chromosome 17 protein; MLLT6, PHD finger domain containing; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog); translocated to, 6; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6; Myeloid/lymphoid or mixed-lineage leukemia, translocated to, 6; myeloid/lymphoid or mixed-lineage leukemia; translocated to, 6; protein AF-17; trithorax homolog

Description (eCommerce)

AF17 was discovered as part of a genetic rearrangement in the MLL (mixed lineage leukemia) gene associated with acute myeloid leukemia.

Gene ID

4302

Gene Name (eCommerce)

MLLT6, PHD finger containing

Gene Name (Vector)

MLLT6, PHD finger domain containing

Gene Symbol

MLLT6

HGNC ID

HGNC:7138

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

1389

ORF Size (bp)

1389 bp

Protein Name (eCommerce)

Protein AF-17

RefSeq ID

NM_005937

RefSeq Synonyms

NM_005937, BC007237,

Research Areas

Cancer,Transcription Factor/Regulator,Zinc-finger

Research Areas (Faceted)

cancer,cell_biology,transcription_translation

Species

human

Target Sentence

AF17 was discovered as part of a genetic rearrangement in the MLL (mixed lineage leukemia) gene associated with acute myeloid leukemia.

UniProt ID (eCommerce)

P55198

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.